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The COVID‑19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID‑19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2). The outbreak was first identified in Wuhan, China, in December 2019. The World Health Organization declared the outbreak a Public Health Emergency of International Concern on 30 ...
Mar 17, 2020· A 100 mg/mL stock solution of AO in ethanol was stored at 4°C and diluted in E3 buffer immediately before use to a final concentration of 5 μg/mL. Zebrafish larvae were incubated in the resulting solution at 28°C for 30 min in the dark, washed twice for 10 min each in E3 buffer, anesthetized in 0.015% tricaine, and mounted in low melting ...
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L ‐Proline‐Catalyzed Asymmetric Direct Aldol Reaction of Heteroaromatic Aldehydes and Acetone: Improvement of Catalytic Efficiency in Ionic Liquid bmim [BF 4 ]. Synthetic Communications 2007, 37 (24) , 4301-4307. DOI: 10.1080/00397910701575574.
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Finance research has a long history of investigating the impact of return skewness on investor decision making. Arditti and Scott and Horvath show that under very general assumptions, investors demonstrate a preference for positive skewness in return distributions.Building on these results, Kraus and Litzenberger and Harvey and Siddique show that an asset's coskewness with the market portfolio ...
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Mar 06, 2020· An ideal tool for gene therapy would enable efficient gene integration at predetermined sites in the human genome. Here we demonstrate biased genome-wide integration of the Sleeping Beauty (SB) transposon by combining it with components of the CRISPR/Cas9 system. We provide proof-of-concept that it is possible to influence the target site selection of SB by fusing it to a catalytically ...
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For each individual stock in the long portfolio, we find the corresponding characteristic-based benchmark portfolio of Daniel et al.(1997) and short it, using the same portfolio weight as the target stock has in HIGHKZ. As in Table 2, in each regression, we omit the portfolio that is the dependent variable from the construction of the ...
Mar 14, 2020· Background. Adolescence is a period involving changes in all areas of life – physical, psychological and social [1, 2].This stage of life is recognised as a second chance at catching up on growth before entering adulthood but is also the stage when body image problems develop as a result of changes associated with physical maturation [] and eating disorder symptoms first emerge [].
Jan 18, 2016· 2.3.1. Fly Stocks and Crosses. The D. melanogaster system was selected for the determination of the safety of B. officinalis consumption as a well-recognized method to analyze vegetable complex mixtures using SMART [31,32].This test was used in order to evaluate the genotoxic and antigenotoxic activity of B. officinalis leaves and petioles as well as their selected bioactive …
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Nov 14, 2007· Summary Appropriate management of urticaria depends on the correct evaluation of clinical patterns and causes where these can be identified. Guidance for treatment is presented, based on the strength of evidence available at the time of preparation. As many of the recommendations relate to the off‐licence use of drugs, it is particularly important that clinicians should be familiar with ...
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Nicotinamide N-methyltransferase (NNMT) catalyzes the methylation of nicotinamide to form N-methylnicotinamide. Overexpression of NNMT is associated with a variety of diseases, including a number of cancers and metabolic disorders, suggesting a role for NNMT as a potential therapeutic target. By structural modification of a lead NNMT inhibitor previously developed in our group, we prepared a ...
10-Q x Quarterly report pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 ... Delaware 47-3335141 (State or Other Jurisdiction of Incorporation or Organization) (I.R.S. Employer ... Indicate the number of shares outstanding of each of the issuer’s classes of common stock, as of the latest practicable date: Class ...
Dong, J. Y. and Qin, L. Q. Soy isoflavones consumption and risk of breast cancer incidence or recurrence: a meta-analysis of prospective studies. Breast Cancer Res.Treat. 2011;125(2):315-323. View ...
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Briefly, strains of S. pneumoniae were grown overnight in BHI from ice stocks and then diluted to an OD 620 of ~0.004 in 20 ml BHI in a 50-ml loosely capped conical tube and were allowed to grow in an atmosphere of 5% CO 2 at 37°C to an optical density of ≈0.1 …
Though most microorganisms live within a community, we have modest knowledge about microbial interactions and their implications for community properties and ecosystem functions. To advance understanding of microbial interactions, we describe a straightforward synthetic community system that can be used to interrogate exometabolite interactions among microorganisms.